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Dr. Ross > Cannabis > What Are the Benefits of Using THC With CBD?

What Are the Benefits of Using THC With CBD?

By: Michele Ross, PhD · Published On: December 20, 2019 · Last Updated: October 4, 2021

In Chronically Cannabis, Dr. Michele Ross, a neuroscientist and cannabis expert, answers The Mighty community’s questions about treating chronic pain with cannabis. This is post #1 of 7 in the series.

The Mighty Community asked: “What are the benefits of using THC in conjunction with CBD, as opposed to just using CBD alone?”

The number one benefit of using THC for chronic pain. THC is more powerful at relieving pain than CBD is. I call CBD by itself, depending on the dosage, kind of like regular Tylenol, and CBD plus THC is like Tylenol Extra Strength.

THC activates your cannabinoid receptors much more strongly than CBD does. In fact, CBD doesn’t even bind to your cannabinoid receptors, it just boosts your natural amount of endocannabinoids, called anandamide. Those bind to your cannabinoid receptors. But anandamide binds much more weakly than THC does.

THC is super powerful at relieving pain, while CBD is a lot more gentle at relieving pain. If you are looking to relieve pain, like very severe pain, there’s only so much CBD can do for you. I hate to say that because a lot of people live in places where cannabis isn’t legal yet. If you take 25 or 50 milligrams of  CBD and expect it to drop your pain from a level 10 to a 4, it’s probably not the case.

Besides the fact that THC more strongly activates those receptors, it also helps an effect called the entourage effect. All the different chemicals that are in the plant, from THC and CBD to other compounds called terpenes, all those components in the plant help your body absorb those cannabinoids better and they’re more likely to actually activate those other receptors and relieve pain and improve mood.

So THC with CBD together is actually more powerful than CBD by itself or THC by itself. THC plus CBD is the magic combination. For chronic pain patients, we recommend a 1 to 1 ratio, which is the same amount of THC and CBD. It’s actually really powerful at reducing inflammation and pain.

That 1-to-1 ratio is interesting because CBD is not psychoactive, it actually balances out the psychoactive components of THC. Sometimes people don’t use THC because they don’t want to get high, but CBD and THC together are very powerful at reducing pain while keeping people relatively in a non-psychoactive zone.

How To Take Action:

Posts #2-7 of this series are now live. Read:

Post #2: Which Cannabis Strains Are Best for Chronic Pain?

Post #3: What Types of Cannabis Products Are Best For Pain?

Post #4: How Does Cannabis Affect Pain Patients WIth Mental Illness?

Post #5: How Do I Try Cannabis If It’s Not Legal?

Post #6: Can You Become Desensitized To Cannabis?

Post #7: How Often Should I Take Cannabis For Pain?

cannabis leaves and stripes

Glossary of Terms

Cannabis: Also known as marijuana, weed, and pot, cannabis is a plant that can be eaten, brewed, smoked and vaporized. Its oils can also be extracted and consumed, or incorporated into topical creams. Cannabis is consumed for its psychoactive and pain-relieving properties. It is currently a Schedule 1 drug in the United States and is illegal at the federal level, but is legal for recreational and/or medical use in 33 states.

THC: Abbreviation for tetrahydrocannabinol, one of the compounds, or “cannabinoids,” found in cannabis. It is responsible for the plant’s psychoactive effects, since it binds to cannabinoid receptors in the brain responsible for pleasure and pain.

CBD: Abbreviation for cannabidiol, another cannabinoid found in cannabis. CBD is non-psychoactive and, unlike THC which binds to cannabinoid receptors, stimulates the body’s own endocannabinoid system. This can lead to physical benefits like reducing pain and lowering inflammation.

Endocannabinoids: Neurotransmitters produced by the body that bind to cannabinoid receptors. Endocannabinoids help control functions like pain and inflammation and maintaining homeostasis in the body.

Strain: A variation of cannabis that has been bred to enhance certain characteristics and compounds.

Terpenes: Aromatic oils secreted by the cannabis plant, which give its particular strain unique flavors and scents. Over 100 types have been identified. Terpenes also interact with other cannabis compounds to produce various physical and psychoactive effects. 

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By: Michele Ross, PhD · In: Cannabis · Tagged: CBD, medical marijuana, thc, the mighty

plant medicine expert neuroscientist Dr. Michele Ross

About Michele Ross, PhD

Dr. Michele Ross is a neuroscientist helping women heal chronic pain with CBD, cannabis, kratom, and mushrooms. She is the author of Kratom is Medicine, Vitamin Weed and CBD Oil For Health.

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Happy International Women's Day to all the women c Happy International Women's Day to all the women crushing it despite getting less pay, less startup funding, less everything when it comes to business. Let's do more than recognize women.
In 2023, it's time to:
*Buy from women-owned businesses
*Give women a seat at the table, preferably the board
*End all male speaking panels
*Invest in women startups, including those focused on serving women
*Include more women in clinical trials
*End toxic work cultures
*Support paid maternity leave policies
*Fill the wage gap between men and women
*Donate to nonprofits serving women
*Let women take time off of work for painful periods without stigma or penalty
*Work harder to specifically include and apply all of these principles to women from marginalized groups such as black women, disabled women, LGBTQ women, and females identifying as nonbinary, genderfluid, or genderqueer.
And so. much. more.
#internationalwomensday #womensday2023 #internationalwomensday2023 #womenfounders
#investinwomen
No one is giving $2 w🌱🌱d gummies to children No one is giving $2 w🌱🌱d gummies to children trick or treating on Halloween. Those reports you hear on the news simply aren’t true! ⁣
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However, if you are attending a Halloween party for adults, ask if the candies, goodies, or drinks are special or infused! Edibles are more common at parties as an alternative to alcohol, especially in states where the plant has been legalized for both recreational & medical use.⁣
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If you’re not used to consuming, try a small piece or half a piece, drink plenty of water, and make sure you have a safe place to sit if needed. And always call a rideshare aka Uber or Lyft home!⁣
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Happy Halloween! 🎃💀👻⁣
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Happy National Mushr00m Day! 🍄 ⁣ Which is you Happy National Mushr00m Day! 🍄
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Which is your favorite Medicinal Mushr00m?⁣⁣
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It's more important than ever to take mushr00m supplements. Here's a little about how my favorite four mushr00ms work:⁣⁣
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Lion’s Mane Mushr00ms: great for improving focus and memory. Lion's mane promotes neurogenesis, or birth of new brain cells.⁣⁣
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Cordyceps Mushr00ms: great for fighting fatigue and increasing length of your workouts. It's especially helpful for fibromyalgia and chronic fatigue patients.⁣⁣
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Turkey Tail Mushr00ms: great for supporting your immune system. Clinical trials have looked at its role in fighting cancer.⁣⁣
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9/20 is National Magic Mushr00m Day. Why have a da 9/20 is National Magic Mushr00m Day. Why have a day to celebrate them?
Well in the United States & many parts of the world, they are still illegal, similar to another misunderstood therapeutic green plant we celebrate on 4/20. 
I've worked hard over the years in Denver & many other states to help decriminalize shr00ms and help people access information on how to use them for medical, spiritual, and stress relief purposes. I suggest following @decriminalizenature & @doubleblindmag for deeper info.
How are you celebrating today? ❤️ 🍄 ❤️
#fungilover #mushroomlover #psychedelictherapy #explorenature #natureistherapy
I’m not the only one, right? 😜 👩🏻‍🔬 💚
As a neuroscientist, I put out the first book on the potential causes of endocannabinoid deficiency and how to balance your ECS with or without plant medicine. 
From stress to medications to diet to your genes, there are so many ways your ECS go go haywire. The fact that so many people respond to plant medicine is likely because so many of us have severe imbalances.
Want to learn more, including what many of these terms mean? Check out my books (including Vitamin Weed) & courses via the link in my bio. 
#sciencelover #cannabiseducation #cannabisscience #lovelanguage #lovelanguages

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